Endocrine Abstracts

Background: TSH secreting pituitary adenomas represent small proportion of functional pituitary tumours presenting as hyperthyroidism with elevated thyroid hormone levels and inappropriately normal or increased TSH concentration. They are ≥1 cm in size and quite aggressive with tendency to relapse following transphenoidal adenomectomy (TSA). Surgical resection remains gold standard in their definitive treatment while pharmacotherapy with long-acting somatostatin analogue...

Introduction: Giant prolactinomas are rare pituitary tumours. They can present with visual field defect, intracranial pressure symptoms and even temporal lobe epilepsy. Impairment of higher cognitive functions has been reported postoperatively after trans-cranial surgery and following radiotherapy. Reversible cognitive disturbances have been previously reported in patients with surgically decompressed arachnoid cysts but not after medical treatment of giant prolactinoma. We pr...